Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
【発明の名称】カリウムチャンネルオープナーの新規用途
Document Type and Number:
Japanese Patent JP2003503447
Kind Code:
A
Abstract:
The use of KCNQ2/3 potassium channel openers to treat neurotransmission, central nervous system, bowel, inflammatory and ophthalmic disorders, and drug-dependence/addition is new. KCNQ2/3 Potassium channel openers are useful as muscle relaxants; anxiolytics; analgesics; antipyretics; treatments for migraine, uni- and bipolar depression, functional bowel disorders, cancer, inflammatory conditions, ophthalmic diseases and tinnitus; and preventing/reducing dependence/tolerance to dependence-inducing agents; and especially as anti-epileptics. ACTIVITY : Anxiolytic; analgesic; antipyretic; anti-migraine; antidepressant; antitinnitus; anticonvulsant; neuroprotective; nootropic; antiparkinsonian; tranquilizer; antiaddictive; antiinflammatory; ophthalmological; cytostatic. MECHANISM OF ACTION : KCNQ2/3 Potassium channel openers and GABA synthesis inducers.

Inventors:
Stephen, Anthony, Barbidge
Jeffrey, John, Claire
Brian cox
Joseph, Dupia
Russell, Michael, Hagan
Jin Min, Gee
Application Number:
JP2001507464A
Publication Date:
January 28, 2003
Filing Date:
June 30, 2000
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
Glaxo Group Limited
International Classes:
A61K45/00; A61K31/00; A61K31/27; A61K31/325; A61P1/04; A61P3/10; A61P5/14; A61P7/06; A61P9/10; A61P11/00; A61P11/06; A61P17/02; A61P17/06; A61P19/02; A61P19/06; A61P21/02; A61P21/04; A61P25/00; A61P25/04; A61P25/08; A61P25/16; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/16; A61P29/00; A61P35/00; A61P43/00; (IPC1-7): A61K45/00; A61K31/27; A61P1/04; A61P3/10; A61P5/14; A61P7/06; A61P9/10; A61P11/00; A61P11/06; A61P17/02; A61P17/06; A61P19/02; A61P19/06; A61P21/02; A61P21/04; A61P25/00; A61P25/04; A61P25/08; A61P25/16; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/16; A61P29/00; A61P35/00; A61P43/00
Attorney, Agent or Firm:
Kenji Yoshitake (3 others)