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Title:
【発明の名称】オピオイド受容体により媒介される痛覚消失を延長および強化するβアレスチン媒介作用の阻害
Document Type and Number:
Japanese Patent JP2003518257
Kind Code:
A
Abstract:
Described are methods of detecting G-protein coupled receptor (GPCR) activity in vivo and in vitro; methods of assaying GPCR activity; and methods of screening for GPCR ligands, G protein-coupled receptor kinase (GRK) activity, and compounds that interact with components of the GPCR regulatory process. Constructs useful in such methods are described.

Inventors:
Bonn, Laura, M.
Lynn, Fang-Twill
Caron, Mark, Gee.
Lefkowitz, Robert, Jay.
Application Number:
JP2001547555A
Publication Date:
June 03, 2003
Filing Date:
December 20, 2000
Export Citation:
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Assignee:
Duke University
International Classes:
A01K67/027; A61K31/485; A61K45/00; A61P25/04; C07K14/47; C12N5/02; C12N15/62; C12N15/85; C12Q1/02; G01N33/15; G01N33/50; G01N33/566; (IPC1-7): G01N33/15; A01K67/027; A61K31/485; A61K45/00; A61P25/04; C12Q1/02; G01N33/50; G01N33/566
Attorney, Agent or Firm:
Yasunori Otsuka (3 others)