Title:
【発明の名称】心血管の病態の予防におけるレニン-アンギオテンシン系阻害剤の使用
Document Type and Number:
Japanese Patent JP2003527325
Kind Code:
A
Abstract:
Use of an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with an other antihypertensive, a cholesterol lowering agent, a diuretic or aspirin, in the manufacture of a medicament for the prevention of cardiovascular events; a method of preventing cardiovascular events comprising administering to a patient in need of such prevention an effective amount of an inhibitor of the renin angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with an other antihypertensive, a cholesterol lowering agent, a diuretic or aspirin; and a combination product containing an an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof and a cholesterol lowering agent.
Inventors:
Bernwald Schelkens
Norbert Bender
Bertrudin Rangoon Walla
Seilim Yusuf
Gilet Dagane
Hazel Gerstein
Norbert Bender
Bertrudin Rangoon Walla
Seilim Yusuf
Gilet Dagane
Hazel Gerstein
Application Number:
JP2001519888A
Publication Date:
September 16, 2003
Filing Date:
August 30, 2000
Export Citation:
Assignee:
Aventis Pharma Deutsche Land Gesellschaft Mitt Beschlenktel Haftung
International Classes:
A61K31/00; A61K31/216; A61K31/355; A61K31/401; A61K31/403; A61K31/404; A61K31/41; A61K31/4166; A61K31/4174; A61K31/4178; A61K31/4184; A61K31/472; A61K31/519; A61K31/55; A61K31/551; A61K31/554; A61K31/612; A61K31/616; A61K31/675; A61K45/06; A61P3/10; A61K45/00; A61P9/04; A61P9/08; A61P9/10; (IPC1-7): A61K45/00; A61K31/216; A61K31/401; A61K31/403; A61K31/404; A61K31/41; A61K31/4166; A61K31/4174; A61K31/4178; A61K31/4184; A61K31/472; A61K31/519; A61K31/55; A61K31/551; A61K31/554; A61K31/612; A61K31/675; A61P3/10; A61P9/04; A61P9/08; A61P9/10
Domestic Patent References:
| JPH07505884A | 1995-06-29 | |||
| JPH1081633A | 1998-03-31 | |||
| JP2003508426A | 2003-03-04 | |||
| JPH01261334A | 1989-10-18 |
Other References:
JPN6010053874, "Ｓｔｕｄｙ ｆｉｎｄｉｎｇｓ ”ｃｏｕｌｄ ｐｒｅｖｅｎｔ ｏｎｅ ｍｉｌｌｉｏｎ ｐｒｅｍａｔｕｒｅ ｄｅａｔｈｓ ｅａｃｈ ｙｅａｒ” ［ｏｎｌｉｎｅ］", ＭｃＭａｓｔｅｒ Ｕｎｉｖｅｒｓｉｔｙ， Ｎｅｗｓ Ｒｅｌｅａｓｅｓ, 19990511
JPN6010053875, "Ｔｈｅ ＨＯＰＥ （Ｈｅａｒｔ Ｏｕｔｃｏｍｅｓ Ｐｒｅｖｅｎｔｉｏｎ Ｅｖａｌｕａｔｉｏｎ） Ｓｔｕｄｙ： ｔｈｅ ｄｅｓｉｇｎ ｏｆ ａ ｌａｒｇｅ， ｓｉｍｐｌｅ ｒａｎｄｏｍｉｚｅｄ ｔｒｉａ", Ｃａｎ Ｊ Ｃａｒｄｉｏｌ, 1996, Ｖｏｌ．１２， Ｎｏ．２, ｐ．１２７−３７
JPN6010053875, "Ｔｈｅ ＨＯＰＥ （Ｈｅａｒｔ Ｏｕｔｃｏｍｅｓ Ｐｒｅｖｅｎｔｉｏｎ Ｅｖａｌｕａｔｉｏｎ） Ｓｔｕｄｙ： ｔｈｅ ｄｅｓｉｇｎ ｏｆ ａ ｌａｒｇｅ， ｓｉｍｐｌｅ ｒａｎｄｏｍｉｚｅｄ ｔｒｉａ", Ｃａｎ Ｊ Ｃａｒｄｉｏｌ, 1996, Ｖｏｌ．１２， Ｎｏ．２, ｐ．１２７−３７
Attorney, Agent or Firm:
Chika Takagi (2 outside)
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