Title:
ステント処理装置および方法
Document Type and Number:
Japanese Patent JP2004524075
Kind Code:
A
Abstract:
Manual stent manipulation before implantation results in foreign body contamination and increased neointimal hyperplasia. Rinsing commercially available sterile stents with high pressure immediately before implantation eliminates residual surface stent contaminants and reduces inflammation elicited by stent struts. Ex-vivo stent expansion and surface analysis revealed that rinsed stents had fewer surface contaminants than untouched or handled stents. In a porcine stent restenosis model, rinsed stents elicited less inflammation and less neointimal hyperplasia at one month than handled and untouched stents. Pressure-rinsing of coronary stents immediately before implantation reduces inflammation and neointimal hyperplasia.
Inventors:
Alan Earl Camrad
Atoni Baes-Jenice
Robert S. Schwartz
Atoni Baes-Jenice
Robert S. Schwartz
Application Number:
JP2002555728A
Publication Date:
August 12, 2004
Filing Date:
January 09, 2002
Export Citation:
Assignee:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
International Classes:
A61F2/82; A61B19/00; A61F2/06; A61F2/84; A61L2/18; A61F2/00; A61F2/90; (IPC1-7): A61M29/00
Attorney, Agent or Firm:
Yoichiro Shimoda