Title:
治療薬としてのF11受容体(F11R)拮抗薬
Document Type and Number:
Japanese Patent JP2006516255
Kind Code:
A
Abstract:
The present invention provides a cell adhesion molecule (CAM), designated F11 receptor (F11R), which is a member of the immunoglobulin super family localized on the surface of human platelets, and determined to effect platelet aggregation, secretion, platelet spreading and cellular adhesion. Cloned F11R cDNA and full length F11R cDNA and amino acid sequences are provided. F11R-antagonists and methods for the prevention and treatment of thrombosis, heart attacks, stroke and other clinical disorders involving thrombus formation are also provided.
Inventors:
Cornecky, Elizabeth
Anna, Babinska
Arrich, Eagle H.
Anna, Babinska
Arrich, Eagle H.
Application Number:
JP2004566554A
Publication Date:
June 29, 2006
Filing Date:
December 16, 2003
Export Citation:
Assignee:
Cornecky, Elizabeth
Anna, Babinska
Arrich, Eagle H.
Anna, Babinska
Arrich, Eagle H.
International Classes:
C07K14/705; A61K38/00; A61K45/00; A61P7/02; A61P9/00; C07K16/28; C12N15/09
Domestic Patent References:
| JP2001509372A | 2001-07-24 |
Foreign References:
| US5665701A | 1997-09-09 |
Attorney, Agent or Firm:
Hidekazu Miyoshi
Masakazu Ito
Masakazu Ito