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Patent Searching and Data


Title:
グリコシル化エンケファリン薬
Document Type and Number:
Japanese Patent JP2006518759
Kind Code:
A
Abstract:
It is taught here that enkephalin peptides which are glycosylated with a disaccharide will be transported across the blood brain barrier and deliver analgesic effects superior to morphine when introduced into the bloodstream. Glycosylated peptides with disaccharides attached are superior to analogous peptides with either mono- or tri-saccharides attached.

Inventors:
ポルト ロビン エル
ビルスキー エドワード ジェイ
Application Number:
JP2006503815A
Publication Date:
August 17, 2006
Filing Date:
February 24, 2004
Export Citation:
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Assignee:
ザ アリゾナ ボード オブ リージェンツ オン ビハーフ オブ ザ ユニヴァーシティ オブ アリゾナ
International Classes:
C07K14/70; A61K9/00; A61K9/08; A61K38/00; A61P25/04; A61P29/00; C07H5/06; C07H7/00; C07H9/00; C07K7/00; C07K9/00; A61K
Foreign References:
Other References:
JPN6009068335, Drugs of the Future,2001,26(6),p.561−76
JPN5006002283, ELMAGBARI, FASEB J., 20010308, V15 N5, P. A915 ABSTRACT #711.1, FEDERATION OF AMERICAN SOC. FOR EXPER. BIOL.
JPN6009068337, J.Org.Chem.,2001,66(7),p.2327−42
Attorney, Agent or Firm:
熊倉 禎男
小川 信夫
箱田 篤
浅井 賢治
平山 孝二