Title:
流体種の形成および制御
Document Type and Number:
Japanese Patent JP2006523142
Kind Code:
A
Abstract:
This invention generally relates to systems and methods for the formation and/or control of fluidic species, and articles produced by such systems and methods. In some cases, the invention involves unique fluid channels, systems, controls, and/or restrictions, and combinations thereof. In certain embodiments, the invention allows fluidic streams (which can be continuous or discontinuous, i.e., droplets) to be formed and/or combined, at a variety of scales, including microfluidic scales. In one set of embodiments, a fluidic stream may be produced from a channel, where a cross-sectional dimension of the fluidic stream is smaller than that of the channel, for example, through the use of structural elements, other fluids, and/or applied external fields, etc. In some cases, a Taylor cone may be produced. In another set of embodiments, a fluidic stream may be manipulated in some fashion, for example, to create tubes (which may be hollow or solid), droplets, nested tubes or droplets, arrays of tubes or droplets, meshes of tubes, etc. In some cases, droplets produced using certain embodiments of the invention may be charged or substantially charged, which may allow their further manipulation, for instance, using applied external fields. Non-limiting examples of such manipulations include producing charged droplets, coalescing droplets (especially at the microscale), synchronizing droplet formation, aligning molecules within the droplet, etc. In some cases, the droplets and/or the fluidic streams may include colloids, cells, therapeutic agents, and the like.
Inventors:
Link, Darren Earl.
Wheats, David A.
Marquez-Sanchez, Maniel
Chen, Chen Dong
Wheats, David A.
Marquez-Sanchez, Maniel
Chen, Chen Dong
Application Number:
JP2006509830A
Publication Date:
October 12, 2006
Filing Date:
April 09, 2004
Export Citation:
Assignee:
President and Fellows of Harvard College
International Classes:
B01J19/00; B01F5/06; B01F13/00; B01J2/04; B01J13/00; B01J19/08; B05B5/03; B05B7/06; G01N37/00
Domestic Patent References:
| JPH0871489A | 1996-03-19 | |||
| JPH10217477A | 1998-08-18 | |||
| JP2001301154A | 2001-10-30 | |||
| JPH08153669A | 1996-06-11 | |||
| JP2002538461A | 2002-11-12 | |||
| JPS62254830A | 1987-11-06 | |||
| JPH03232525A | 1991-10-16 | |||
| JP2001517353A | 2001-10-02 | |||
| JP2003501257A | 2003-01-14 |
Foreign References:
| WO2002068104A1 | 2002-09-06 | |||
| WO2001080283A1 | 2001-10-25 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita