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Patent Searching and Data


Title:
薬剤の肺投与の方法
Document Type and Number:
Japanese Patent JP2007500239
Kind Code:
A
Abstract:
A method for administering a therapeutic or diagnostic agent to a subject is described. The method includes providing a suspension of liposomes comprised of one or more of vesicle-forming lipids selected from (i) a vesicle-forming lipid derivatized with a hydrophilic polymer and (ii) a neutral lipopolymer, said liposomes being associated with said therapeutic or diagnostic agent, forming an aerosol of said liposome suspension; and administering the aerosol to the subject by inhalation. The liposome formulation delivers intact liposomal particles to the respiratory tract of said subject to form a depot of therapeutic agent therein with no observable provocation of an immune response, as measured by neutrophil or macrophage cell count in the lung after administration.

Inventors:
ウオング,フランセス・エム・ピー
ダス,アヌク
セイドマン,ジヨナサン
グオ,リユーク
フアング,アンソニー
Application Number:
JP2006533501A
Publication Date:
January 11, 2007
Filing Date:
May 27, 2004
Export Citation:
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Assignee:
アルザ・コーポレーシヨン
International Classes:
A61K47/34; A61K9/00; A61K9/12; A61K9/127; A61K9/72
Attorney, Agent or Firm:
小田島 平吉