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Title:
治療応答を誘導するための組成物
Document Type and Number:
Japanese Patent JP2007525444
Kind Code:
A
Abstract:
Compositions for attracting specific cells to an in vivo site and for stimulating the attracted cells and local resident cells to achieve a desired therapy are described. In one embodiment, a composition for initiating and promoting repair and regeneration of tissue is described. In another embodiment, a composition for inducing a cytotoxic response to tumor cells is described. The compositions are comprised of drug reservoirs containing one or more therapeutic agents effective (1) to attract one or more desired cells to the tissue site; (2) to stimulate activity, e.g., proliferation, differentiation, and/or release of biological factors that promote a desired activity, in the attracted cells; and (3) to prolong survival of the attracted cells and, if desired, local resident cells. A device for administering the composition at a desired site is also described.

Inventors:
フロイクス, マイケル
ブルスゼウスキー, ウォルター
Application Number:
JP2006509414A
Publication Date:
September 06, 2007
Filing Date:
March 25, 2004
Export Citation:
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Assignee:
ヘリコニア コーポレイション
International Classes:
A61K45/06; A61K38/00; A61K38/18; A61K38/19; A61K38/20; A61K38/22; A61L29/00; A61M25/00; A61P1/16; A61P1/18; A61P9/00; A61P21/00; A61P25/00; A61P35/00; A61P37/04; A61P43/00
Domestic Patent References:
JPS57118512A1982-07-23
JP2000501084A2000-02-02
Foreign References:
WO2000060054A12000-10-12
WO2002058723A22002-08-01
US5328471A1994-07-12
US6152141A2000-11-28
Attorney, Agent or Firm:
山本 秀策
安村 高明
森下 夏樹