Title:
置換フェニルアルカン酸
Document Type and Number:
Japanese Patent JP2008518926
Kind Code:
A
Abstract:
The present invention relates to compounds and pharmaceutically acceptable salts of formula I: which are useful in the treatment of metabolic disorders related to insulin resistance or hyperglycemia. These compounds include inhibitors of protein tyrosine phosphatase (PTP-1B) that are useful in the treatment of diabetes and other PTP-1B mediated diseases, such as cancer, neurodegenerative diseases and the like. The compounds of the invention are also useful in pharmaceutical compositions and methods of treating the aforementioned conditions.
Inventors:
Vanzant, Michael, Sea.
Fan, Hai Quan
Fu, Xiao Jin
White House, Darren
Fan, Hai Quan
Fu, Xiao Jin
White House, Darren
Application Number:
JP2007539167A
Publication Date:
June 05, 2008
Filing Date:
October 28, 2005
Export Citation:
Assignee:
The Institute for Pharmaceutical Discovery, LRC
International Classes:
C07C311/21; A61K31/196; A61K31/4406; A61P3/10; A61P25/00; A61P25/28; A61P35/00; A61P43/00; C07D213/55
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda