Title:
RHO-キナーゼの阻害剤としてのイソキノリン誘導体
Document Type and Number:
Japanese Patent JP2008543956
Kind Code:
A
Abstract:
The invention relates to 6-piperidinyl-substituted isoquinoline derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
Inventors:
Oliver Plettenburg
Armin Hofmeister
Dieter Cardellite
Stephan Poikert
Sven Ruff
Kurt Ritter
Matthias Lane
Yuri Ivashchenko
Peter Monecke
Matthias Dryer
Aimo Kant
Armin Hofmeister
Dieter Cardellite
Stephan Poikert
Sven Ruff
Kurt Ritter
Matthias Lane
Yuri Ivashchenko
Peter Monecke
Matthias Dryer
Aimo Kant
Application Number:
JP2008518659A
Publication Date:
December 04, 2008
Filing Date:
June 13, 2006
Export Citation:
Assignee:
Sanofi-Aventis
International Classes:
C07D401/12; A61K31/4725; A61K31/496; A61K31/506; A61K31/5377; A61P1/16; A61P3/10; A61P7/02; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P11/16; A61P13/08; A61P13/12; A61P15/06; A61P15/10; A61P19/10; A61P25/00; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P31/04; A61P31/18; A61P35/00; A61P37/02; A61P43/00; C07D401/14; C07D405/14; C07D409/14; C07D413/14
Domestic Patent References:
| JP2005232175A | 2005-09-02 |
Foreign References:
| WO2004009555A1 | 2004-01-29 | |||
| WO2002100833A1 | 2002-12-19 |
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi