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Title:
新規化合物
Document Type and Number:
Japanese Patent JP2009506979
Kind Code:
A
Abstract:
This invention relates to novel amide derivatives and salts thereof. More particularly, it relates to novel amide derivatives and salts thereof which act as a ROCK inhibitor, to a pharmaceutical composition comprising the same and to a method of using the same therapeutically in the treatment and/or prevention of ROCK-related disease.

Inventors:
澤田 弘造
善光 龍哉
寺澤 武志
今村 佳正
福留 裕樹
黒田 聡
前田 純
渡辺 順子
井波 寛
竹下 暢昭
Application Number:
JP2008510929A
Publication Date:
February 19, 2009
Filing Date:
August 29, 2006
Export Citation:
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Assignee:
アステラス製薬株式会社
International Classes:
C07D213/40; A61K31/4418; A61K31/443; A61K31/4436; A61K31/4439; A61K31/444; A61K31/4709; A61K31/4725; A61K31/505; A61K31/506; A61K31/5377; A61K31/541; A61P3/10; A61P9/08; A61P9/10; A61P9/12; A61P11/06; A61P13/08; A61P13/10; A61P15/10; A61P17/06; A61P19/02; A61P19/10; A61P21/04; A61P25/04; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P31/12; A61P37/02; A61P43/00; C07D213/75; C07D239/42; C07D401/12; C07D401/14; C07D403/04; C07D405/12; C07D409/12; C07D417/12
Domestic Patent References:
JP2005029517A2005-02-03
JPS5711965A1982-01-21
JP2004520299A2004-07-08
JPH10513442A1998-12-22
JP2008509982A2008-04-03
Foreign References:
WO2006051311A12006-05-18
WO2005003101A22005-01-13
US4376775A1983-03-15
FR2530246A11984-01-20
WO2002030880A22002-04-18
WO1999042455A11999-08-26
WO2004016597A22004-02-26
Other References:
JPN7012003193; DATABASE CHEMCATS [Online]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US , Accession No.2006:5028782
JPN7012003194; J. Med. Chem. Vol.12, No.2, 1969, pp.199-206
JPN7012003186; Journal of the Chemical Society No.Part II, 1940, pp.1279-1284
JPN7012003187; Synthesis No.12, 2004, pp.1996-2000
JPN7012003195; J. Med. Chem. Vol.40, No.22, 1997, pp.3542-3550
JPN7012003196; J. Med. Chem. Vol.11, 1968, pp.963-966
JPN7012003189; Journal of the American Chemical Society Vol.80, 1958, pp.2205-2217
JPN7012003190; Tetrahedron Letters Vol.39, 1998, pp.4453-4454
JPN7012003191; Synthetic Communications Vol.13, No.11, 1983, pp.951-958
JPN7012003192; J. Med. Chem. Vol.11, 1968, pp.295-300
Attorney, Agent or Firm:
森田 拓
矢野 恵美子
鈴木 ▲頼▼子
濱井 康丞