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Title:
細胞内のPRL-1ポリペプチドまたはPRL-3ポリペプチドに結合する抗体
Document Type and Number:
Japanese Patent JP2010530735
Kind Code:
A
Abstract:
We provide an antibody capable of binding to an intracellular PRL-1 or PRL-3 polypeptide, in which the antibody is capable of binding to an epitope bound by an antibody 269, antibody 223 or antibody 318. Such anti-PRL antibodies may be capable of binding to intracellular PRL-1 or PRL-3. They may be suitable for use as therapies against cancer or metastasis thereof, or in clinical diagnosis to identify PRL-3 or PRL-1 positive patients.

Inventors:
Zen
Application Number:
JP2010506146A
Publication Date:
September 16, 2010
Filing Date:
May 03, 2008
Export Citation:
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Assignee:
AGENCY FOR SCIENCE,TECHNOLOGY AND RESEARCH
International Classes:
C12N15/09; A61K31/7088; A61K39/395; A61P35/00; C07K16/18; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; G01N33/574; G01N33/577; A01K67/027; C12N9/99; C12P21/08
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka