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Title:
11β-ヒドロキシステロイドデヒドロゲナーゼI型を阻害するのに有用な6置換スルホニルアザビシクロ[3.2.1]オクタン
Document Type and Number:
Japanese Patent JP2010536750
Kind Code:
A
Abstract:
In its many embodiments, the present invention relates to a novel class of 6-substituted sulfonyl-1,3,3-trialkyl-6-azabicyclo[3.2.1]octane compounds useful to inhibit 11beta-hydroxysteroid dehydrogenase type-I, pharmaceutical compositions containing the compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the expression of 11beta-hydroxysteroid dehydrogenase type-I using such compounds or pharmaceutical compositions.

Inventors:
Boyle, Craig Dee.
Chakkala Manil, Samuel
Rankin, Claire M.
Shah, Yun Messy.
Application Number:
JP2010521002A
Publication Date:
December 02, 2010
Filing Date:
August 12, 2008
Export Citation:
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Assignee:
Schering Corporation
International Classes:
C07D209/02; A61K31/403; A61K31/4155; A61K31/422; A61K31/433; A61K31/44; A61K31/5377; A61K31/5395; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P43/00; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12; C07D499/893; C07D499/897
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita