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Document Type and Number:
Japanese Patent JP2607485
Kind Code:
A bicyclic naphthalenic compound has the formula (I) wherein A represents methylene or dimethylene, substituted or not by lower alkyl, R1, R2, R3 and R4 represent hydrogen or lower alkyl, or R1 and R3 taken together form a methylene or dimethylene bridge when A represents dimethylene, R' represents hydrogen, OH, alkoxy having 1-4 carbon atoms, acyloxy having 1-4 carbon atoms or amino, R'' represents hydrogen or alkoxy having 1-4 carbon atoms, or r' and R'' taken together form an oxo, methano or hydroxyimino group, R represents -CH2OH or -COR5, R5 represents hydrogen, -OR6 or R6 represents hydrogen, alkyl having 1-20 carbon atoms, monohydroxyalkyl, polyhydroxyalkyl, aryl or aralkyl optionally substituted, the residue of a sugar or p is 1, 2 or 3, and r' and r'', each independently, represent hydrogen, lower alkyl, monohydroxyalkyl optionally interrupted by a heteroatom, polyhydroxyalkyl, aryl or benzyl optionally substituted, the residue of an amino acid, an aminoester or an aminated sugar, or r' and r'' together form with the nitrogen atom to which they are attached, a heterocycle substituted or not, and the salts of said compounds of formula (I) or the optional isomers thereof.

Application Number:
Publication Date:
May 07, 1997
Filing Date:
October 11, 1986
Export Citation:
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International Classes:
A61K8/00; A61K8/30; A61K8/34; A61K8/36; A61K8/368; A61K8/37; A61K8/42; A61K8/49; A61K31/045; A61K31/11; A61K31/12; A61K31/135; A61K31/15; A61K31/165; A61K31/19; A61K31/195; A61K31/215; A61K31/22; A61K31/235; A61K31/445; A61K31/585; A61P17/00; A61P35/00; A61P43/00; C07C63/36; A61Q5/00; A61Q19/00; C07C33/34; C07C33/36; C07C33/38; C07C41/00; C07C43/178; C07C43/30; C07C45/00; C07C45/30; C07C47/445; C07C47/546; C07C47/56; C07C47/57; C07C49/83; C07C49/86; C07C51/00; C07C63/49; C07C63/66; C07C65/17; C07C65/26; C07C65/36; C07C67/00; C07C69/76; C07C213/00; C07C215/28; C07C217/48; C07C223/02; C07C229/38; C07C233/12; C07C233/64; C07C233/65; C07C235/66; C07C235/84; C07C237/30; C07C239/00; C07C251/48; C07C259/10; C07C323/59; C07D295/18; C07H15/18; C07H15/20; C07C; (IPC1-7): C07C33/34; A61K7/06; A61K31/045; A61K31/11; A61K31/12; A61K31/15; A61K31/165; A61K31/19; A61K31/195; A61K31/235; A61K31/445; C07C47/57; C07C49/86; C07C63/49; C07C65/17; C07C65/26; C07C65/36; C07C69/145; C07C69/76; C07C229/38; C07C233/65; C07C235/66; C07C251/40
Attorney, Agent or Firm:
八木田 茂 (外2名)

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