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Title:
【発明の名称】白金錯体およびこれらを有効成分として含有する抗腫瘍剤
Document Type and Number:
Japanese Patent JP2740919
Kind Code:
B2
Abstract:
Novel platinum complexes of the formula: wherein R<1> and R<2> are identical or different lower alkyl groups, or R<1> and R<2> taken together form a -(CH2)m- bridge, and m is an integer from 2 to 5, and antitumor agents comprising the compounds (I) are disclosed, which are effective against cisplatin-resistant ascitic murine leukemia, murine leukemia, and solid tumors with only slight hemotoxicity and nephrotoxicity.

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Inventors:
Toshishi Toya
Osamu Shiratori
Yoshihiro Muraoka
Application Number:
JP8091789A
Publication Date:
April 15, 1998
Filing Date:
March 30, 1989
Export Citation:
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Assignee:
Shionogi Pharmaceutical Co., Ltd.
International Classes:
A61K31/28; A61K31/282; A61K33/24; A61P35/00; C07C59/01; C07C62/02; C07C62/04; C07C211/36; C07C211/65; C07F15/00; (IPC1-7): C07F15/00; A61K31/28; A61K33/24; C07C211/65
Attorney, Agent or Firm:
Hiromitsu Takayama