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Patent Searching and Data


Title:
ジヒドロピリミジン類およびその使用
Document Type and Number:
Japanese Patent JP3200070
Kind Code:
B2
Abstract:
This invention is directed to the use of dihydropyrimidine compounds, which are selective antagonists for cloned human alpha1C receptors, for the treatment of benign prostatic hyperplasia and other diseases where antagonism of the human alpha1C receptor is useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-identified compounds and a pharmaceutically acceptable carrier.

Inventors:
ウォン、ワイ・シー
グルチョウスキー、チャールズ
ダール、ティー・ジー・ムラリー
チュウ、ジョージ
ナガラスナム、ダーナパラン
マルザバディー、モハマッド・アール
ミャオ、ショウ・ウー
ラグー、バーラット
Application Number:
JP51635496A
Publication Date:
August 20, 2001
Filing Date:
November 16, 1995
Export Citation:
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Assignee:
シナプティック・ファーマスーティカル・コーポレーション
International Classes:
C07D239/22; A61K31/505; A61K31/506; A61P3/06; A61P9/06; A61P13/02; A61P13/08; A61P15/00; A61P25/04; A61P43/00; C07D239/30; C07D401/06; C07D401/12; C07D401/14; C07D403/12; C07D405/14; C07D413/14; C07D453/02; C07D491/04; C07D491/048; C07D521/00; A61K; C07D; (IPC1-7): C07D239/22; A61K31/505; A61K31/506; A61P13/02; A61P13/08; A61P43/00; C07D401/06; C07D401/12; C07D401/14; C07D413/14; C07D453/02; C07D491/048
Other References:
Journal of Medicinal Chemistry;vol.35(No.17)p3254−3263(1992)
Journal of Organic Chemistry;vol.54(No.25)p5898−5907(1989)
Tetrahedron Letters;vol.32(No.10),p5405−5408(1988)
Attorney, Agent or Firm:
鈴江 武彦 (外4名)