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Document Type and Number:
Japanese Patent JP3362394
Kind Code:
The use of a medium-chain fatty acid triglyceride as the dispersant in the preparation of a medicinal aerosol composition comprising tricyclic compound (I) dispersed in a liquefied hydrofluoroalkane propellant is described. When a liquefied hydrofluoroalkane is added to a kneaded premix of the tricyclic compound (I) and a medium-chain fatty acid triglyceride, the active ingredient is evenly dispersed in the liquefied hydrofluoroalkane. Therefore, by distributing a dispenser first with the kneaded premix and, then, with a liquefied hydrofluoroalkane under cooling or elevated pressure, there can be provided a medicinal aerosol composition having an improved uniformity of content of the active ingredient.

下条 文男
徳永 雄二
村田 三郎
秦 武久
Application Number:
Publication Date:
January 07, 2003
Filing Date:
September 18, 1996
Export Citation:
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International Classes:
A61K9/12; A61K9/00; A61K31/135; A61K31/137; A61K31/35; A61K31/407; A61K31/425; A61K31/436; A61K31/4433; A61K31/4525; A61K31/46; A61K31/47; A61K31/57; A61K31/573; A61K38/00; A61K45/00; A61K47/06; A61K47/14; A61P11/00; A61P11/08; A61P31/04; A61P37/06; A61P43/00; C07D498/18; (IPC1-7): A61K31/407; A61K9/12; A61K31/436; A61K47/06; A61K47/14; A61P31/04; A61P37/06
Attorney, Agent or Firm:
田伏 英治

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