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Title:
マピア・ホエチダからのアルカロイド及び抗ウイルス剤を含む製剤
Document Type and Number:
Japanese Patent JP3615240
Kind Code:
B2
Abstract:
The present invention relates to novel alkaloids from Mappia foetida, foetidine 1 and 2, having anticancer and antiviral properties. These alkaloids, soluble in water, are present in all the parts of the plant, and are the precursors of camptothecin and of 9-methoxy-camptothecin, which are alkaloids known to have pharmacodynamic properties but also to be insoluble in water. The particular water solubility of the novel compounds make them particularly suitable for the treatment of the patients by the parenteral route, avoiding the use of toxic excipients or of unsuitable chemical derivatizations.

Inventors:
エツィオ・ボンバルデッリ
ジュセッペ・ムステッチ
ルイセルラ・ヴェロッタ
Application Number:
JP17254294A
Publication Date:
February 02, 2005
Filing Date:
July 25, 1994
Export Citation:
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Assignee:
INDENA SOCIETA PER AZIONI
International Classes:
C07D487/14; A61K31/12; A61K31/35; A61K31/435; A61K31/4453; A61K31/4523; A61K31/47; A61K31/4745; A61K31/475; A61K35/00; A61K36/18; A61K36/185; A61P31/12; A61P31/18; A61P31/22; A61P35/00; C07D471/12; C07D471/14; C07D487/12; (IPC1-7): C07D471/14
Domestic Patent References:
JP6501476A
Foreign References:
WO1994011377A2
Attorney, Agent or Firm:
津国 肇
渡邉 睦雄
篠田 文雄