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Title:
抗痙攣性を示すソルボピラノーススルファメート類
Document Type and Number:
Japanese Patent JP3621097
Kind Code:
B2
Abstract:
The present invention relates to a method of preparing BCH-189 and various analogues of BCH-189 from inexpensive precursors with the option of introducing functionality as needed. This synthetic route allows the stereoselective preparation of the biologically active isomer of these compounds, beta -BCH-189 and related compounds. Furthermore, the stereochemistry at the nucleoside 4'-position can be controlled to produce enantiomerically-enriched beta -BCH-189 and its analogues.

Inventors:
Costanzo, Michael Jei
Marianov, Bruce Yee
Application Number:
JP51521294A
Publication Date:
February 16, 2005
Filing Date:
December 07, 1993
Export Citation:
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Assignee:
McNee Love Incorporated
International Classes:
A61K31/70; A61K31/7048; A61K31/76; A61P1/06; A61P13/06; A61P25/08; C07D493/04; C07D493/14; C07H9/04; C07H11/00; C07H13/00; C07H13/06; (IPC1-7): C07H9/04; A61K31/70; A61P1/06; A61P13/06; C07D493/04; C07D493/14; C07H13/06
Domestic Patent References:
JP60109558A
Foreign References:
Attorney, Agent or Firm:
Heiyoshi Odashima