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Title:
神経障害性疼痛の処置に有用の鎮痙性誘導体
Document Type and Number:
Japanese Patent JP4097294
Kind Code:
B2
Abstract:
The present invention describes a method for treating neuropathic pain comprising administering to a mammal afflicted with such condition a therapeutically effective amount for treating such condition of a compound of formula (I), wherein: X is CH2 or oxygen; R1 is hydrogen or alkyl; and R2, R3, R4 and R5 are independently hydrogen or lower alkyl and, when X is CH2, R4 and R5 may be alkene groups joined to form a benzene ring and, when X is oxygen, R2 and R3 and/or R4 and R5 together may be a methylenedioxy group of formula (II), wherein R6 and R7 are the same or different and are hydrogen, lower alkyl or are alkyl and are joined to form a cyclopentyl or cyclohexyl ring, particularly topiramate.

Inventors:
シヤンク, リチヤード・ピー
ワイルド, ケネス
Application Number:
JP51749098A
Publication Date:
June 11, 2008
Filing Date:
July 16, 1997
Export Citation:
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Assignee:
オーソ―マクニール・フアーマシユーチカル・インコーポレーテツド
International Classes:
A61K31/70; A61P25/04; A61K31/16; A61K31/18; A61K31/34; A61K31/35; A61K31/351; A61K31/352; A61P25/02; C07H9/04; C07C307/02; C07D309/06; C07H11/00
Domestic Patent References:
JP2001500121A
JP60109558A
Attorney, Agent or Firm:
小田島 平吉
小田嶋 平吾