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Title:
4’-C-置換-2-ハロアデノシン誘導体
Document Type and Number:
Japanese Patent JP4253342
Kind Code:
B2
Abstract:
The present invention provides a 4'-C-substituted-2-haloadenosine derivative represented by the following formula ÄIÜ, ÄIIÜ, or ÄIIIÜ: (wherein X represents a halogen atom, R<1> represents an ethynyl group or a cyano group, and R<2> represents hydrogen, a phosphate residue, or a phosphate derivative residue). The present invention also provides a pharmaceutical composition containing the derivative and a pharmaceutically acceptable carrier therefor.

Inventors:
Satoru Kogo
Great Western
Eiichi Kodama
Matsuoka Masao
Hiroaki Mitsuya
Application Number:
JP2006511319A
Publication Date:
April 08, 2009
Filing Date:
March 24, 2005
Export Citation:
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Assignee:
Yamasa Shoyu Co., Ltd.
International Classes:
C07H19/173; A61K31/7076; A61P31/18; A61P43/00; C07H19/16
Domestic Patent References:
JP2001335592A
JP2001335593A
Foreign References:
US5192749
WO2003068796A1
Other References:
Daniela Salvatori, Rosaria Volpini, Silvia Vincenzetti, Alberto Vita, Stefano Costanzi, Catia Lambertucci, Gloria Cristalli and Sauro Vittori,Adenine and Deazaadenine Nucleoside and Deoxynucleoside Analogues: Inhibition of Viral Replication of Sheep MVV (In Vitro Model for HIV) and Bovine BHV-1,Bioorganic & Medicinal Chemistry,英国,Elsevier Science;Oxford,2002年 7月,Vol.10, Issue 9,2973-2980
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto