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Title:
ミデカマイシン高生産菌
Document Type and Number:
Japanese Patent JP4633519
Kind Code:
B2
Abstract:
A midecamycin hyper producing strain having improved productivity of midecamycin which is a member of macrolide antibiotics, and a method for producing midecamycins using the strain are provided. The midecamycin producing actinomycetes comprises a midecamycin biosynthesis gene or a homologue thereof, wherein at least one module in a polyketide synthase gene of a midecamycin biosynthesis gene or partial sequences of the at least one module, is substituted so as to encode the corresponding amino acid sequences of the other module.

Inventors:
渡辺 学
中橋 正晃
Application Number:
JP2005101836A
Publication Date:
February 23, 2011
Filing Date:
March 31, 2005
Export Citation:
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Assignee:
明治製菓株式会社
International Classes:
C12N1/21; C12P19/62; C12N15/09; C12R1/465
Domestic Patent References:
JP2004049100A
Attorney, Agent or Firm:
小栗 昌平
本多 弘徳
市川 利光