Title:
方法
Document Type and Number:
Japanese Patent JP4652665
Kind Code:
B2
Abstract:
The molecules of formula (1) are useful in treating diabetes, obesity, hypercholesterolaemia, hyperlipidaemia, cancer, inflammation of other conditions in which modulation of lipid or eicosanoid status or functions may be desirable. Formula (1): Z 1 -X-Z 2 wherein (a) Z 1 represents CO 2 H or a derivative thereof; (b) Z 2 represents F, H, -CO 2 H or a derivative thereof; and (c) X represents fluorinated alkylene; or a solvate thereof, for example a perfluorinated fatty acid or derivative thereof.
Inventors:
Elcombe, Clifford Roy
Wolf, charles roland
Wolf, charles roland
Application Number:
JP2002565586A
Publication Date:
March 16, 2011
Filing Date:
February 18, 2002
Export Citation:
Assignee:
CXR Biosciences Limited
International Classes:
A61K31/20; G01N33/50; A23L1/30; A23L33/00; A61K31/19; A61K31/23; A61K45/00; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P9/10; A61P11/00; A61P15/00; A61P19/02; A61P29/00; A61P35/00; C12Q1/02; C12Q1/26; C12Q1/42; G01N33/15; G01N33/92
Foreign References:
| WO1992011248A1 | ||||
| US4624851 |
Other References:
XENOBIOTICA,1993年,23(7),P.761-770
CARCINOGENESIS,1990年,11(11),P.1899-1902
SCHEDIN, S.,BIOCHEMICAL PHARMACOLOGY,1998年,V56N9,P1195-1199
OKOCHI, E.,BIOCHIMICA ET BIOPHYSICA ACTA,1999年 1月27日,V1437N3,P393-401
GEN. PHARMACOL.,1998年,31(2),P.187-197
TOXICOL. APPL. PHARMACOL.,1999年,161(2),P.209-218
BORGES, T.,ARCHIVES OF TOXICOLOGY,1990年,V64N1,P26-30
KEES, K. L.,JOUNRAL OF MEDICINAL CHEMISTRY,1992年,V35,P944-953
TRIVEDI, B. K.,JOURNAL OF MEDICINAL CHEMISTRY,1989年,V32,P11-13
CIMINI, A.,BIOCHIMICA ET BIOPHYSICAA ACTA,2000年 2月29日,V1474N3,P397-409
CARCINOGENESIS,1990年,11(11),P.1899-1902
SCHEDIN, S.,BIOCHEMICAL PHARMACOLOGY,1998年,V56N9,P1195-1199
OKOCHI, E.,BIOCHIMICA ET BIOPHYSICA ACTA,1999年 1月27日,V1437N3,P393-401
GEN. PHARMACOL.,1998年,31(2),P.187-197
TOXICOL. APPL. PHARMACOL.,1999年,161(2),P.209-218
BORGES, T.,ARCHIVES OF TOXICOLOGY,1990年,V64N1,P26-30
KEES, K. L.,JOUNRAL OF MEDICINAL CHEMISTRY,1992年,V35,P944-953
TRIVEDI, B. K.,JOURNAL OF MEDICINAL CHEMISTRY,1989年,V32,P11-13
CIMINI, A.,BIOCHIMICA ET BIOPHYSICAA ACTA,2000年 2月29日,V1474N3,P397-409
Attorney, Agent or Firm:
Mijiro Abe