Title:
インドリノン誘導体の製造方法
Document Type and Number:
Japanese Patent JP5269907
Kind Code:
B2
Abstract:
The present invention relates to a process for the manufacture of a specific indolinone derivative and a pharmaceutically acceptable salt thereof, namely 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone and its monoethanesulfonate, to new manufacturing steps and to new intermediates of this process.
Inventors:
Melten Jerun
Linz Gunther
Schnaubbert juergen
SCHMID,Rolf
Lahr Werner
Renner Svenya
Reichel Karsten
Schieffers Robert
Linz Gunther
Schnaubbert juergen
SCHMID,Rolf
Lahr Werner
Renner Svenya
Reichel Karsten
Schieffers Robert
Application Number:
JP2010535406A
Publication Date:
August 21, 2013
Filing Date:
December 02, 2008
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D209/34; C07D295/14
Domestic Patent References:
| JP2003511441A | ||||
| JP2006501273A | ||||
| JP2002525356A | ||||
| JP2005535684A |
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Matsuda Nanae
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Matsuda Nanae