Title:
ブタ浮腫病ワクチン
Document Type and Number:
Japanese Patent JP5279089
Kind Code:
B2
Abstract:
A technology for producing a pig edema disease vaccine at low cost and at high efficiency is developed. Specifically, a gene of a pig edema disease toxin protein (Stx2e protein) is efficiently expressed in plant cells to produce a plant vaccine for pig edema disease at low cost. An Stx2e protein including a secretory signal peptide derived from a plant added at an amino terminus is expressed in cells of a plant such as Lactuca sativa using the 5'-untranslated region of an alcohol dehydrogenase gene (ADH5'UTR) derived from a plant.
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Inventors:
Kazutoshi Sawada
Kazuya Yoshida
Takeshi Matsui
Makino Soichi
Keiko Kawamoto
Kazuya Yoshida
Takeshi Matsui
Makino Soichi
Keiko Kawamoto
Application Number:
JP2009521546A
Publication Date:
September 04, 2013
Filing Date:
March 25, 2008
Export Citation:
Assignee:
IDEMITSU KOSAN CO.,LTD.
Nara Institute of Science and Technology
Obihiro University of Agriculture and Veterinary Medicine
Nara Institute of Science and Technology
Obihiro University of Agriculture and Veterinary Medicine
International Classes:
C12N15/09; A01H5/00; A01H5/10; A01H6/14; A61K35/74; A61K35/76; A61K39/108; A61P31/04; A61P39/02; C12N5/10; C12N15/82
Domestic Patent References:
| JP2003116385A | 2003-04-22 | |||
| JPH09505467A | 1997-06-03 | |||
| JP2003180354A | 2003-07-02 | |||
| JPH0549482A | 1993-03-02 | |||
| JP2004506432A | 2004-03-04 | |||
| JP2006515169A | 2006-05-25 | |||
| JP2006524506A | 2006-11-02 | |||
| JP2003116385A | 2003-04-22 | |||
| JPH09505467A | 1997-06-03 | |||
| JP2003180354A | 2003-07-02 | |||
| JPH0549482A | 1993-03-02 | |||
| JP2004506432A | 2004-03-04 | |||
| JP2006515169A | 2006-05-25 |
Foreign References:
| WO2001052886A1 | 2001-07-26 | |||
| WO2001052886A1 | 2001-07-26 |
Other References:
JPN7013000009; Ｐｒｏｔｅｉｎ Ｅｘｐｒ．Ｐｕｒｉｆ． Ｖｏｌ．５１， Ｎｏ．１, 200701, ｐｐ．２２-２７
JPN7013000010; Ａｐｐｌ． Ｂｉｏｃｈｅｍ． Ｂｉｏｔｅｃｈｎｏｌ． Ｖｏｌ．１１７， Ｎｏ．３, 2004, ｐｐ．１７５-１８７
JPN6008019694; Ｊ． Ｂｉｏｓｃｉ． Ｂｉｏｅｎｇ． Ｖｏｌ．１０２， Ｎｏ．２, 200608, ｐｐ．１０２-１０９
JPN6008019442; Ｍｉｃｒｏｂ． Ｐａｔｈｏｇ． Ｖｏｌ．３１， Ｎｏ．１, 2001, ｐｐ．１-８
JPN6008019444; Ｐｒｏｔｅｉｎ Ｅｘｐｒ． Ｐｕｒｉｆ． Ｖｏｌ．５１， Ｎｏ．１, 200701, ｐｐ．２２-２７
JPN7013000010; Ａｐｐｌ． Ｂｉｏｃｈｅｍ． Ｂｉｏｔｅｃｈｎｏｌ． Ｖｏｌ．１１７， Ｎｏ．３, 2004, ｐｐ．１７５-１８７
JPN7013000010; Ａｐｐｌ． Ｂｉｏｃｈｅｍ． Ｂｉｏｔｅｃｈｎｏｌ． Ｖｏｌ．１１７， Ｎｏ．３, 2004, ｐｐ．１７５-１８７
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JPN6008019442; Ｍｉｃｒｏｂ． Ｐａｔｈｏｇ． Ｖｏｌ．３１， Ｎｏ．１, 2001, ｐｐ．１-８
JPN6008019444; Ｐｒｏｔｅｉｎ Ｅｘｐｒ． Ｐｕｒｉｆ． Ｖｏｌ．５１， Ｎｏ．１, 200701, ｐｐ．２２-２７
JPN7013000010; Ａｐｐｌ． Ｂｉｏｃｈｅｍ． Ｂｉｏｔｅｃｈｎｏｌ． Ｖｏｌ．１１７， Ｎｏ．３, 2004, ｐｐ．１７５-１８７
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Tsutomu Toyama
Shinichi Sanuki
Tomoko Tsujida
Tsutomu Toyama
Shinichi Sanuki
Tomoko Tsujida