Title:
前立腺関連抗原およびワクチンに基づく免疫療法レジメン
Document Type and Number:
Japanese Patent JP6434905
Kind Code:
B2
Abstract:
The present disclosure provides (a) isolated immunogenic PAA polypeptides; (b) isolated nucleic acid molecules encoding immunogenic PAA polypeptides; (c) vaccine compositions comprising an immunogenic PAA polypeptide or an isolated nucleic acid molecule encoding an immunogenic PAA polypeptide; (d) methods relating to uses of the polypeptides, nucleic acid molecules, and compositions; and (e) vaccine-based immunotherapy regimens which involve co-administration of a vaccine in combination with an immune-suppressive-cell inhibitor and an immune-effector-cell enhancer.
Inventors:
Joseph John Binder
Helen Kim Cho
Michael robert darmier
Karin Ute Yosu
Brian Gregory Pearce
Joyce Twitan
Van to Tusai
Helen Kim Cho
Michael robert darmier
Karin Ute Yosu
Brian Gregory Pearce
Joyce Twitan
Van to Tusai
Application Number:
JP2015509541A
Publication Date:
December 05, 2018
Filing Date:
April 29, 2013
Export Citation:
Assignee:
Pfizer Inc.
International Classes:
C07K14/705; A61K31/404; A61K31/7088; A61K35/76; A61K38/00; A61K39/00; A61K39/395; A61K45/00; A61K48/00; A61P13/08; A61P35/00; A61P37/02; A61P43/00; C12N15/12
Other References:
Bernadette Ferraro et al.,Co-delivary of PSA and PSMA DNA vaccines with electroporation induces potent immune responses,Human Vaccines,2011年,Vol. 7 Suppl.,pp.120-127
YING WAECKERLE-MEN,DENDRITIC CELL-BASED MULTI-EPITOPE IMMUNOTHERAPY OF HORMONE-REFRACTORY PROSTATE CARCINOMA,CANCER IMMUNOLOGY, IMMUNOTHERAPY,ドイツ,2006年 4月13日,Vol.55, No.12,pp.1524-1533
Accession No: Q04609, Definition: Glutamate carboxypeptidase 2 ,Database: uniprot [online],1994年 6月 1日, [retrieved on 2017-03-27]
OLSON WILLIAM C. et al.,CLINICAL TRIALS OF CANCER THERAPIES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN,REVIEWS OF RECENT CLINICAL TRIALS,2007年 9月,Vol.2, No.3,pp.182-190
YING WAECKERLE-MEN,DENDRITIC CELL-BASED MULTI-EPITOPE IMMUNOTHERAPY OF HORMONE-REFRACTORY PROSTATE CARCINOMA,CANCER IMMUNOLOGY, IMMUNOTHERAPY,ドイツ,2006年 4月13日,Vol.55, No.12,pp.1524-1533
Accession No: Q04609, Definition: Glutamate carboxypeptidase 2 ,Database: uniprot [online],1994年 6月 1日,
OLSON WILLIAM C. et al.,CLINICAL TRIALS OF CANCER THERAPIES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN,REVIEWS OF RECENT CLINICAL TRIALS,2007年 9月,Vol.2, No.3,pp.182-190
Attorney, Agent or Firm:
Noh four
Junko Miyazawa
Maki Sato
Tatsuta Miyuki
Junko Miyazawa
Maki Sato
Tatsuta Miyuki