Title:
舌下用アポモルフィン
Document Type and Number:
Japanese Patent JP6506381
Kind Code:
B2
Abstract:
The present invention relates to a pharmaceutical composition in unit dosage form formulated for sublingual administration, wherein said unit dosage form has a first portion comprising apomorphine particles comprising an acid addition salt of apomorphine and a second portion comprising a pH neutralizing agent, wherein the unit dosage from comprises a polymer selected from carboxymethylcellulose, cellulose acetate, ethylcellulose, hydroxyethylcellulose, hydroxypropylmethylcellulose, nitrocellulose, polyoxyethylene/polyoxypropylene polymers, copolymers or block copolymers, polyvinylpyrrolidone polymers or derivatives, gums and combinations thereof.
Inventors:
Giovinazzo, Anthony, John
Heden, david, blues
De Somer, Marc, Elle.
Bryson, Nathan, John
Heden, david, blues
De Somer, Marc, Elle.
Bryson, Nathan, John
Application Number:
JP2017244979A
Publication Date:
April 24, 2019
Filing Date:
December 21, 2017
Export Citation:
Assignee:
Sanovion Pharmaceuticals, Inc.
International Classes:
A61K31/473; A61K9/20; A61K9/70; A61K47/02; A61K47/06; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/20; A61K47/22; A61K47/26; A61K47/32; A61K47/36; A61P15/00; A61P25/16; A61P25/24
Domestic Patent References:
| JP2016147882A | ||||
| JP8034731A | ||||
| JP2006508122A | ||||
| JP2006523703A |
Foreign References:
| CN1460476A |
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Natsuo Tanaka
Naoko Kikuta
Hiramatsu Chiharu
Satoshi Fujita
Natsuo Tanaka
Naoko Kikuta
Hiramatsu Chiharu