Login| Sign Up| Help| Contact|

Patent Searching and Data

Document Type and Number:
Japanese Patent JP6643239
Kind Code:
Disclosed herein are nanoparticles containing MERS virus proteins in polymer structures, and compositions containing the nanoparticles formulated for administration as immunogenic compositions. Also provided herein are vector constructs encoding the proteins, and host cells containing the vector constructs. The disclosure also includes methods of making the nanoparticles and administering them to vertebrates, including methods of inducing immune responses to MERS that reduce or prevent infection by the virus.

Smith, Gale
Riu, Ye
Masale, Michael
Application Number:
Publication Date:
February 12, 2020
Filing Date:
September 19, 2014
Export Citation:
Click for automatic bibliography generation   Help
Nova Bucks, Inc.
International Classes:
A61K39/215; A61K39/395; A61P31/14; C07K14/165; C07K16/08
Other References:
NOVAVAX,STIFEL 2013 HEALTHCARE CONFERENCE,[ONLINE],2013年 9月12日,URL,http://www.novavax.com/download/file/2013_09_12%20Novavax_Stifel_presentation.pdf
Novavax creates MERS-CoV vaccine candidate,Vaccine News daily,2013年 6月 7日,URL,https://vaccinenewsdaily.com/stories/510534663-novavax-creates-mers-cov-vaccine-candidate
DELMAS, B., et al.,J. Virology, 1990, Vol.64, No.11, pp.5367-5375
Vaccine, 2011, Vol.29, pp.6606-6613
J. Virology, 2013.08, Vol.87, No.21, pp.11950-11954
COTTEN, M. et al., 'S protein [Middle East respiratory syndrome coronavirus]' DATABASE NCBI Protein, [online], accession No.AGN70973, 10-Jun-2013, [retrieved on 2018.06.13],URL,https://www.ncbi.nlm.nih.gov/protein/511261317?sat=18&satkey=14547166
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito