Title:
抗−ヒトＩＬ−３抗体、ＩＬ−３の高められた発現又はレベルに関連する疾患又は機能障害へのそれらの使用、及びヒトＩＬ−３の検出方法へのそれらの使用
Document Type and Number:
Japanese Patent JP6845237
Kind Code:
B2
Abstract:
Anti-human interleukin 3 (IL-3) antibodies or fragments thereof according to the present invention are useful as therapeutic agents. The antibodies can be used in pharmaceutical compositions for the treatment or prevention of diseases which are associated with elevated expression or levels of human IL-3 in a patient, especially inflammatory or autoimmune diseases, such as rheumatoid arthritis. The antibodies can also be used to detect human IL-3 expressed by human cells.
Inventors:
Matthias Mac
Hirke Bruhl
Kerstin Renner
Hirke Bruhl
Kerstin Renner
Application Number:
JP2018525399A
Publication Date:
March 17, 2021
Filing Date:
November 10, 2016
Export Citation:
Assignee:
Unibelcitate Skrnikum Regensburg
International Classes:
C07K16/24; A61K39/395; A61P17/00; A61P19/02; A61P21/00; A61P25/00; A61P29/00; A61P37/06; C12N15/06; C12N15/13; G01N33/53
Foreign References:
| WO2013178707A1 | ||||
| WO2013178706A1 | ||||
| WO2015063228A1 |
Other References:
Journal of Immunological Methods,1991年,Vol.145,p.161-165
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Jun Tsuruta
Tomohiro Minamiyama
Yoichi Watanabe
Naori Kota
Shinji Mitsuhashi
Jun Tsuruta
Tomohiro Minamiyama
Yoichi Watanabe
Naori Kota