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Patent Searching and Data


Title:
混合シクロデキストリン種を担持するポリロタキサン、およびその使用
Document Type and Number:
Japanese Patent JP6852080
Kind Code:
B2
Abstract:
Various embodiments of the present invention are directed to polyrotaxanes comprising a poloxamer core and at least one cyclodextrin and methods for treating Niemann-Pick type C (NPC) and imaging (e.g., MRI) using the polyrotaxanes of the various embodiments of the present invention.

Inventors:
Thompson David H.
Hyunsuk-hee
Monji Nou Yao
Collins Christopher
Application Number:
JP2018539241A
Publication Date:
March 31, 2021
Filing Date:
October 14, 2016
Export Citation:
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Assignee:
PURDUE RESEARCH FOUNDATION
International Classes:
C08G65/333; A61K31/724; A61K47/69; A61K51/06; A61P3/00; C08K5/1545; C08L71/02
Foreign References:
WO2014182804A1
Other References:
Yawo A. Mondjinou et al.,Biomacromolecules,2013年,Vol.14,pp.4189-4197
Atsushi Tamura et al.,Scientific Reports,2014年 3月12日,4:4356,pp.1-8
Christopher J. Collins et al.,Biochemistry,2013年,Vol.52,pp.3242-3253
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto