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Document Type and Number:
Japanese Patent JP6890836
Kind Code:
The present disclosure provides a pharmaceutical association for use in the treatment, prevention and/or diagnostic of a neoplastic disease, said association comprising at least one growth factor receptor-binding compound, which activates at least one growth factor receptor of a neoplastic cell, and at least one bioactive carrier forming at least one covalent or non-covalent interaction with said at least one growth factor receptor-binding compound, and wherein said association reduces or suppresses, in the neoplastic cell, the gene expression of at least one cyclin D and/or reduces or suppresses the formation of at least one complex formed between said at least one cyclin D and at least one of cyclin dependent-kinase 4 or 6.

Zuani, Omar F.
Gocheva, Veronica
Application Number:
Publication Date:
June 18, 2021
Filing Date:
September 15, 2016
Export Citation:
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Histoid Akzien Gezel Shaft
International Classes:
A61K38/03; A61K38/08; A61K38/16; A61K38/18; A61K47/52; A61K47/56; A61K47/59; A61P35/00; A61P43/00; C12N5/09; C12Q1/02; G16B15/30
Domestic Patent References:
Foreign References:
Attorney, Agent or Firm:
Atomi International Patent Office