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Title:
高M6P組換えタンパク質の選択方法
Document Type and Number:
Japanese Patent JP7046003
Kind Code:
B2
Abstract:
Methods for the production, capturing and purification of recombinant human lysosomal proteins are described. Such recombinant human lysosomal proteins can have high content of mannose-6-phosphate residues. Also described are pharmaceutical compositions comprising such recombinant human lysosomal proteins, as well as methods of treatment and uses of such recombinant human lysosomal proteins.

Inventors:
Do, Han Vee.
Gotzchor, Russell
Application Number:
JP2018551350A
Publication Date:
April 01, 2022
Filing Date:
March 30, 2017
Export Citation:
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Assignee:
Amicus Therapeutics Incorporated
International Classes:
C12N9/26; A61K31/7008; A61K38/47; A61K45/00; A61P3/08; A61P43/00; C07K1/18; C07K1/22; C07K1/36; C12N5/10; C12N15/56
Domestic Patent References:
JP2015516148A
JP2008545657A
JP2011514152A
JP2002531581A
Other References:
Biochemistry and Molecular Biology International,1997年,Vol.43, No.3,pp.613-623
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation