Title:
新規な免疫刺激マクロライド
Document Type and Number:
Japanese Patent JP7100653
Kind Code:
B2
Abstract:
The present invention provides immune stimulating macrolides of formula (I), wherein the substituents are as defined in the claims. The macrolides have utility in treating viral diseases and cancer.
Inventors:
Bink Vist, Aura
Lind, Emma
Berlin, Robert
Gregory, Matt
Moss, Stephen
Lind, Emma
Berlin, Robert
Gregory, Matt
Moss, Stephen
Application Number:
JP2019544838A
Publication Date:
July 13, 2022
Filing Date:
February 22, 2018
Export Citation:
Assignee:
Immune System Regulation Holding Aktiebolag (Pable)
International Classes:
C07H17/08; A61K31/7052; A61P31/12; A61P31/18; A61P35/00; C12P19/62
Foreign References:
| WO2008028050A1 | ||||
| WO2005054265A1 | ||||
| WO2005054266A1 |
Other References:
URSULA SCHELL,ENGINEERED BIOSYNTHESIS OF HYBRID MACROLIDE POLYKETIDES CONTAINING D-ANGOLOSAMINE 以下備考,ORGANIC & BIOMOLECULAR CHEMISTRY,英国,2008年,VOL:6,NR:18,PAGE(S):3315-3327,http://dx.doi.org/10.1039/b807914e,AND D-MYCAMINOSE MOIETIES
PAULETTE COLLUM,3-O-(2′′,6′′-DIDEOXY-α-L-RIBO-HEXOPYRANOSYL)-ERYTHRONOLIDE B AND 3-O-(2′′,6′′,DIDEOXY-以下備考,TETRAHEDRON,NL,1976年,VOL:32, NR:20,PAGE(S):2375 - 2378,http://dx.doi.org/10.1016/0040-4020(76)87017-2,α-L-ARABINO-HEXOPYRANOSYL)ERYTHRONOLIDE B, ABERRANT ERYTHROMYCIN BIOGENETIC 以下省略
JERRY R MARTIN,STUDIES ON THE BIOSYNTHESIS OF THE ERYTHROMYCINS. I. ISOLATION AND STRUCTURE OF AN 以下備考,BIOCHEMISTRY,米国,1966年09月,VOL:5, NR:9,PAGE(S):2852 - 2856,http://dx.doi.org/10.1021/bi00873a011,INTERMEDIATE GLYCOSIDE, 3-α-L-MYCAROSYLERYTHRONOLIDE B *
SVETLANA A BORISOVA,GLYCOSYLATION OF ACYCLIC AND CYCLIC AGLYCONE SUBSTRATES BY MACROLIDE GLYCOSYL以下備考,CHEMBIOCHEM,ドイツ,2008年07月02日,VOL:9, NR:10,PAGE(S):1554 - 1558,http://dx.doi.org/10.1002/cbic.200800155,TRANSFERASE DESVII/DESVIII: ANALYSIS AND IMPLICATIONS
ZHANG CHANGSHENG,THE IN VITRO CHARACTERIZATION OF THE ERYTHRONOLIDE MYCAROSYLTRANSFERASE ERYBV AND 以下備考,CHEMBIOCHEM,ドイツ,2007年03月,VOL:8, NR:4,PAGE(S):385 - 390,http://dx.doi.org/10.1002/cbic.200600509,ITS UTILITY IN MACROLIDE DIVERSIFICATION
PAULETTE COLLUM,3-O-(2′′,6′′-DIDEOXY-α-L-RIBO-HEXOPYRANOSYL)-ERYTHRONOLIDE B AND 3-O-(2′′,6′′,DIDEOXY-以下備考,TETRAHEDRON,NL,1976年,VOL:32, NR:20,PAGE(S):2375 - 2378,http://dx.doi.org/10.1016/0040-4020(76)87017-2,α-L-ARABINO-HEXOPYRANOSYL)ERYTHRONOLIDE B, ABERRANT ERYTHROMYCIN BIOGENETIC 以下省略
JERRY R MARTIN,STUDIES ON THE BIOSYNTHESIS OF THE ERYTHROMYCINS. I. ISOLATION AND STRUCTURE OF AN 以下備考,BIOCHEMISTRY,米国,1966年09月,VOL:5, NR:9,PAGE(S):2852 - 2856,http://dx.doi.org/10.1021/bi00873a011,INTERMEDIATE GLYCOSIDE, 3-α-L-MYCAROSYLERYTHRONOLIDE B *
SVETLANA A BORISOVA,GLYCOSYLATION OF ACYCLIC AND CYCLIC AGLYCONE SUBSTRATES BY MACROLIDE GLYCOSYL以下備考,CHEMBIOCHEM,ドイツ,2008年07月02日,VOL:9, NR:10,PAGE(S):1554 - 1558,http://dx.doi.org/10.1002/cbic.200800155,TRANSFERASE DESVII/DESVIII: ANALYSIS AND IMPLICATIONS
ZHANG CHANGSHENG,THE IN VITRO CHARACTERIZATION OF THE ERYTHRONOLIDE MYCAROSYLTRANSFERASE ERYBV AND 以下備考,CHEMBIOCHEM,ドイツ,2007年03月,VOL:8, NR:4,PAGE(S):385 - 390,http://dx.doi.org/10.1002/cbic.200600509,ITS UTILITY IN MACROLIDE DIVERSIFICATION
Attorney, Agent or Firm:
Asamura patent office
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