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Title:
デングウイルス複製阻害剤としての置換インドリン誘導体
Document Type and Number:
Japanese Patent JP7179773
Kind Code:
B2
Abstract:
The present invention concerns substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.

Inventors:
Bonfanti, Jean-Francois
Kestel Inn, Bad, Rudolph, Romany
Birdiet, dolote, alice, marie-eve
Marchand, Arnaud, Didier, Em
Coorsman's, Irwin
De Beck, Benoit, Christian, Alberto, Ghislain
La Boisson, Pierre, Jean-Marie, Bernard
Application Number:
JP2019564452A
Publication Date:
November 29, 2022
Filing Date:
May 18, 2018
Export Citation:
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Assignee:
Janssen Pharmaceuticals, Incorporated
Catholic Universitette Leuven
International Classes:
C07D209/10; A61K31/404; A61K31/407; A61K45/00; A61P31/12; A61P31/14; A61P43/00; C07D209/30; C07D209/32; C07D495/04
Domestic Patent References:
JP2014527978A
JP2012500267A
JP2016520537A
JP6970115B2
Foreign References:
WO2016050841A1
WO2016113371A1
WO2017046255A1
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Junko Kobayashi
Norio Omori
Ryo Hoshikawa
Yasuhito Suzuki