Title:
スキルス性胃癌の治療剤、及び胃癌の予後の予測方法
Document Type and Number:
Japanese Patent JP7203447
Kind Code:
B2
Abstract:
To provide a scirrhous gastric cancer therapeutic agent that shows excellent therapeutic effect on scirrhous gastric cancer.SOLUTION: It has been found that CXCL1, CXCR2, CCL20, CCR6, and Lipocalin-2 are involved in a signal that induces a bone marrow stromal cell to a stroma of scirrhous gastric cancer, and the inhibition of expression and/or function of these molecules allows scirrhous gastric cancer to be effectively treated.SELECTED DRAWING: None
Inventors:
Hirose Hirakawa
Masakazu Yatsushiro
Hiroaki Kasashima
Masayuki Hino
Hirohisa Nakamae
Takahiko Nakane
Masakazu Yatsushiro
Hiroaki Kasashima
Masayuki Hino
Hirohisa Nakamae
Takahiko Nakane
Application Number:
JP2021073627A
Publication Date:
January 13, 2023
Filing Date:
April 23, 2021
Export Citation:
Assignee:
Public University Corporation Osaka
International Classes:
G01N33/574
Domestic Patent References:
| JP2009515148A |
Foreign References:
| EP1777523A1 | ||||
| WO2014100434A1 |
Other References:
W-L Cheng et al.,Overexpression of CXCL1 and its receptor CXCR2promote tumor invasion in gastric cancer,Ann Oncol.,Oxford University Press,2011年02月22日,22(10),2267-2276,DOI: 10.1093/annonc/mdq739,Web検索
Attorney, Agent or Firm:
Junya Tanaka
Kaguya Mizutani
Kyoko Sakoda
Kaguya Mizutani
Kyoko Sakoda
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