Document Type and Number:
Japanese Patent JPH0478625
Kind Code:
B2
Abstract:
Novel compounds have a formula (I)
wherein
represents a bicyclo [2,2,1] hept-2Z-ene, bicyclo [2,2,1] heptane, 7-oxa-bicyclo [2,2,1] hept-2Z-ene, 7-oxa-bicyclo [2,2,1] heptane, bicyclo [2,2,2] oct-2Z-ene or bicyclo [2,2,2] octane substituted at the 5-position by the group R<1> and at the 6-position by the group ANR<2>R, a 6,6-dimethyl-bicyclo [3,1,1] heptane substituted at the 2-position by the group R<1> and at the 3-position by the group ANR<2>R or at the 2-position by the group ANR<2>R and at the 3-position by the group R<1>, a cyclohex-1-ene or cyclohexane substituted at the 4-position by the group R<1> and at the 5-position by the group ANR<2>R or a 1-hydroxycyclopentane substituted at the 2-position by the group R<1> and at the 2-position by the group ANR<2>R, R<1> is a 6-carboxyhex-2-enyl group or a modification thereof as defined herein; A is an unbranched or branched aliphatic hydrocarbon group with a chain length between the points of attachment to the divalent cyclic group and to the group NR<2>R of 1 to 5 carbon atoms or such a group substituted by an aromatic group; R<2> is hydrogen, an aliphatic hydrocarbon group, an aromatic group or an aliphatic hydrocarbon group substituted by an aromatic group or groups, and R is a group -CO.NR<3>R<4>, -CS.NR<3>R<4>, -CNH.NR<3>R<4>, -CO.R<4> or -CS.R<4> in which R<3> is hydrogen, an aliphatic hydrocarbon group, an aromatic group or an aliphatic hydrocarbon group substituted by an aromatic group or groups, and R<4> is an aliphatic hydrocarbon group, an aromatic group or an aliphatic hydrocarbon group substituted directly by an aromatic.
Inventors:
ROBAATO RESURII JOONZU
NOOMAN HATSUPAA UIRUSON
NOOMAN HATSUPAA UIRUSON
Application Number:
JP9183487A
Publication Date:
December 11, 1992
Filing Date:
April 14, 1987
Export Citation:
Assignee:
NAT RES DEV
International Classes:
C07C59/74; A61K31/16; A61K31/17; A61K31/195; A61K31/215; A61K31/557; A61P7/02; A61P11/08; A61P29/00; C07C43/315; C07C45/44; C07C51/00; C07C59/325; C07C59/353; C07C59/62; C07C59/80; C07C59/86; C07C67/00; C07C69/608; C07C69/716; C07C69/738; C07C229/28; C07C229/32; C07C231/00; C07C233/05; C07C233/65; C07C235/06; C07C235/20; C07C235/46; C07C237/24; C07C239/00; C07C275/26; C07C275/28; C07C335/16; C07C401/00; C07C405/00; C07D213/55; C07D277/62; C07D307/00; C07D493/00; C07D493/08
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