Document Type and Number:
Japanese Patent JPH051257
Kind Code:
B2
Abstract:
Novel arginine derivatives represented by the general formula wherein R1 stands for a naphthalenesulfonyl, a naphthalenecarbonyl, a 1,2,3,4-tetrahydronaphthalenesulfonyl, a 1,2,3,4-tetrahydronaphthalenecarbonyl, a dioxa b-6,7-naphthalenesulfonyl, a dioxa b-6,7-naphthalenecarbonyl, a 1,2,3,4-tetrahydro-8-quinolinesulfonyl, a 1,2,3,4-tetrahydro-8-quinolinecarbonyl, a dibenzofuransulfonyl, a dibenzofurancarbonyl, a fluorenesulfonyl, a fluorenecarbonyl, a dibenzothiophenesulfonyl or a dibenzothiophene, and R2 stands for a piperidino or a piperazino are disclosed. These arginine derivatives and their pharmaceutically acceptable salts have trypsin-inhibiting activity and useful as a pancreatitis remedy.
Inventors:
KIKUMOTO RYOJI
TAMAO YOSHIKUNI
TONOMURA SHINJI
MARUYAMA AKIRA
OKAMOTO AKYOSHI
OKUMYA AKIKO
TAMAO YOSHIKUNI
TONOMURA SHINJI
MARUYAMA AKIRA
OKAMOTO AKYOSHI
OKUMYA AKIKO
Application Number:
JP1980084A
Publication Date:
January 07, 1993
Filing Date:
February 06, 1984
Export Citation:
Assignee:
MITSUBISHI CHEM IND
International Classes:
C07D295/18; A61K31/4427; A61K31/443; A61K31/445; A61K31/451; A61K31/47; A61P43/00; C07C67/00; C07C239/00; C07C279/04; C07C301/00; C07C311/18; C07D211/14; C07D211/16; C07D211/22; C07D211/46; C07D211/60; C07D211/64; C07D215/36; C07D295/185; C07D319/00; C07D319/22; C07D401/12; C07D405/12; C07K5/072; A61K38/00
Next Patent: JPH051258