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Document Type and Number:
Japanese Patent JPH07504425
Kind Code:
A
Abstract:
PCT No. PCT/FR93/00224 Sec. 371 Date Sep. 26, 1994 Sec. 102(e) Date Sep. 26, 1994 PCT Filed Mar. 8, 1993 PCT Pub. No. WO93/17997 PCT Pub. Date Sep. 16, 1993This invention relates to a method for preparing beta -phenylisoserine and analogues thereof having general formula (I) (I) from an aromatic aldehyde and an alpha -methylarylamine-S, and through a lactam of general formula (II) as described herein. The acids of general formula (I) (R=H) may be used to prepare taxane derivatives having remarkable antitumoral and antileukaemic activity.

Application Number:
JP51539493A
Publication Date:
May 18, 1995
Filing Date:
March 08, 1993
Export Citation:
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International Classes:
C07C227/18; C07C227/22; C07C229/34; C07D205/08; C07D305/14; (IPC1-7): C07C229/34; C07C227/18; C07D305/14



 
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