Title:
【発明の名称】多重翻訳開始部位から多量体タンパク質を発現出来るレトロウイルスベクター
Document Type and Number:
Japanese Patent JPH08510636
Kind Code:
A
Abstract:
This invention relates to retroviral vectors that express multiple polypeptide subunits of a eukaryotic protein from a single polycistronic mRNA and the proteins produced from these vectors. The expressed proteins are particularly useful for inducing transplantation tolerance and the vectors are useful as agents for mediating gene transfer into eukaryotic cells.
Inventors:
Lugan, Christian A.
Seed, brian
Bannergie, Peas Tea.
Seed, brian
Bannergie, Peas Tea.
Application Number:
JP51253894A
Publication Date:
November 12, 1996
Filing Date:
January 17, 1994
Export Citation:
Assignee:
Biotransplant, Incorporated
The General Hospital Corporation
The General Hospital Corporation
International Classes:
A61K31/70; A61K35/12; A61K35/76; A61K38/00; A61K48/00; A61P37/06; C07K14/74; C12N5/10; C12N7/01; C12N15/79; C12N15/867; C12P21/02; C12N15/09; C12R1/91; C12R1/92; (IPC1-7): C12N15/09; C12N5/10; C12P21/02
Attorney, Agent or Firm:
Hiroyuki Niwa