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Patent Searching and Data


Title:
【発明の名称】慢性関節リウマチを治療するための方法および試薬
Document Type and Number:
Japanese Patent JPH10500679
Kind Code:
A
Abstract:
Methods useful in the treatment or prevention of rheumatoid arthritis (RA) are disclosed. Each method is useful in limiting the exposure of the systemic immune system of a human to RA arthritogenic peptides present in the person's gastrointestinal (GI) tract. To this end, one method of the invention reduces the population of arthritogenic peptide producing bacteria in the GI tract, then replaces those bacteria with ones incapable of producing the arthritogenic peptides. Methods for both passive and active immunization of a human against arthritogenic peptides are disclosed, as is a method for identifying persons who are predisposed to develop RA.

Inventors:
Carson, Denise A.
Salvator, Albany
Application Number:
JP53028895A
Publication Date:
January 20, 1998
Filing Date:
April 24, 1995
Export Citation:
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Assignee:
The Regents of the University of California
International Classes:
A61K38/00; A61K35/74; A61K35/744; A61K38/22; A61K39/395; A61K39/40; A61K45/00; A61P29/00; A61P37/00; C07K14/245; C07K14/74; C07K16/04; C07K16/12; A61K39/00; A61K48/00; (IPC1-7): A61K35/74; A61K38/00; A61K38/22; A61K39/395; A61K45/00
Attorney, Agent or Firm:
Atsushi Nakajima (2 outside)