Title:
【発明の名称】NSAIDの超微粒子を含んで成る組成物
Document Type and Number:
Japanese Patent JPH10513198
Kind Code:
A
Abstract:
A composition comprising a crystalline NSAID having polyvinylpyrrolidone adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm, hygroscopic sugar and sodium lauryl sulfate exhibit greatly reduced gastric irritation following oral administration and/or hastened onset of action due to the substantial redispersion of the solid formulation to nanoparticles in gastric fluid.
Inventors:
Eikhoff, W., Mark
The Engers, David A.
Mueller, Karl Earl.
The Engers, David A.
Mueller, Karl Earl.
Application Number:
JP52426896A
Publication Date:
December 15, 1998
Filing Date:
January 18, 1996
Export Citation:
Assignee:
Nano Systems Limited Liability Company
International Classes:
A61K9/50; A61K9/14; A61K9/16; A61K9/18; A61K31/19; A61K31/405; A61K31/60; A61K47/30; A61P29/00; (IPC1-7): A61K9/50; A61K31/19; A61K31/405; A61K31/60; A61K47/30
Attorney, Agent or Firm:
Takashi Ishida (3 others)