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Title:
3,5,6-SUBSTITUTED DERIVATIVES OF 1,2-O-ISOPROPYLYDENE-ALPHA,D-GLUCOFURANOSE AND INTERMEDIATES FOR PREPARING THESE DERIVATIVES
Document Type and Number:
Japanese Patent JPH03163091
Kind Code:
A
Abstract:

NEW MATERIAL: Compounds of the formula (R1 is H, C4-11 alkoxyl, hydroxyl residue, aralkyl having at least 7C, etc.; R2 is H, C4-7 alkoxy, methylthiocarbonyl, etc.; R3 is H, halogen alkylene, aralkyl having at least 7C, etc.).

EXAMPLE: 1,2:3,5-di-O-isopropylidene-6-deoxy-6-amino-heptyl-α,D-glucofuranose.

USE: Drug for the treatment of autoimmune deficiency syndrome, acabies, etc.

PROCESS: 1,2:3,5-di-O-isopropylidene-6-tosyl-α,D-glucofuranose as the starting material is suspended in NaOH, refluxed, and extracted and the obtained compd. is added with p-toluensulfonyl chloride in anhydrous pyridine, extracted, added further with 1-aminoheptane, extracted and purified.


Inventors:
BURUUSU ROOZEN
SUUDAASHIYAN KEE ARORA
ARUBAATO BUI TOOMASU
Application Number:
JP16296890A
Publication Date:
July 15, 1991
Filing Date:
June 22, 1990
Export Citation:
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Assignee:
GURIINUITSUCHI PHARMACEUT INC
International Classes:
A61K31/70; A61P29/00; A61P37/00; A61P37/08; C07H9/00; C07H9/04; C07H15/12; C07H15/14; (IPC1-7): A61K31/70; C07H9/04
Attorney, Agent or Firm:
Aoki Akira (3 outside)



 
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