Title:
55 AMINO 77 FUENIRU 2*33 JIHIDORO 1HH1*44 JIAZEPIN OYOBI SONOJUDOTAINOSEIZOHOHO
Document Type and Number:
Japanese Patent JPS5136482
Kind Code:
A
Abstract:
Novel 5-amino-7-phenyl-2,3-dihydro-1H-1,4-diazepines of the formula I are prepared. R1, R2 and R3 are, independently of one another, hydrogen, an alkyl group with 1-4 carbon atoms, an alkoxy group with 1-4 carbon atoms, fluorine, chlorine or bromine, or two of the substituents R1, R2 and R3, which are located on adjacent carbon atoms, represent a methylenedioxy group. The compounds of the formula Ia in which R1 is t-butyl are heated in the presence of free acid for this purpose. The compounds are active against obesity and have an antidiabetic effect. 5-Amino-7-phenyl-2,3-dihydro-1H-1,4-diazepine is preferred.
Inventors:
UIRIAMU RONARUDO JEI SHINPUSON
Application Number:
JP3615775A
Publication Date:
March 27, 1976
Filing Date:
March 27, 1975
Export Citation:
Assignee:
SANDOZ AG
International Classes:
C07D243/08; C07D401/04; C07D403/04; C07D405/10; (IPC1-7): A61K31/55; C07D403/04; C07D403/14; C07D405/10; C07D405/14