5,6-EPOXY-7-OXABICYCLOHEPTANE SUBSTITUTED PROSTAGLANDIN ANALOGUE

Title:

5,6-EPOXY-7-OXABICYCLOHEPTANE SUBSTITUTED PROSTAGLANDIN ANALOGUE

Document Type and Number:

Japanese Patent JPS61271290

Kind Code:

A

Abstract:

5,6-Epoxy-7-oxabicycloheptane substituted prostaglandin analogs are provided having the structural formulawherein m is 1 to 5, R is H, lower alkyl, alkali metal or polyhydroxylamine, and R' is lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl or lower alkenyl, including all stereoisomers thereof.The compounds are cardiovascular agents useful, for example, in the treatment of thrombotic disease.

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Inventors:

JIYAGABANDEYUU DASU

Application Number:

JP11711886A

Publication Date:

December 01, 1986

Filing Date:

May 20, 1986

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Assignee:

SQUIBB & SONS INC

International Classes:

A61K31/557; A61P7/02; A61P9/08; A61P9/10; A61P11/08; C07D493/18; (IPC1-7): A61K31/557; C07D303/00; C07D307/00; C07D493/18

Attorney, Agent or Firm:

Aoyama

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