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Title:
5,6-EPOXY-7-OXABICYCLOHEPTANE SUBSTITUTED PROSTAGLANDIN ANALOGUE
Document Type and Number:
Japanese Patent JPS61271290
Kind Code:
A
Abstract:
5,6-Epoxy-7-oxabicycloheptane substituted prostaglandin analogs are provided having the structural formulawherein m is 1 to 5, R is H, lower alkyl, alkali metal or polyhydroxylamine, and R' is lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl or lower alkenyl, including all stereoisomers thereof.The compounds are cardiovascular agents useful, for example, in the treatment of thrombotic disease.

Inventors:
JIYAGABANDEYUU DASU
Application Number:
JP11711886A
Publication Date:
December 01, 1986
Filing Date:
May 20, 1986
Export Citation:
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Assignee:
SQUIBB & SONS INC
International Classes:
A61K31/557; A61P7/02; A61P9/08; A61P9/10; A61P11/08; C07D493/18; (IPC1-7): A61K31/557; C07D303/00; C07D307/00; C07D493/18