Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
ACETAMINOPHEN CONJUGATES, COMPOSITIONS AND METHODS OF USE THEREOF
Document Type and Number:
Japanese Patent JP2018131447
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide acetaminophen conjugates, and to provide compositions and methods of use thereof.SOLUTION: Acetaminophen conjugates are provided, which have an acetaminophen moiety covalently linked to a second moiety. The conjugates provided may have one or more advantageous properties, including increased water solubility as compared to acetaminophen, reduced toxicity profile as compared to acetaminophen and an altered pharmacokinetic profile. Formulations comprising the conjugates are also provided, as well as methods of using the conjugates and kits comprising the conjugates.SELECTED DRAWING: None

Inventors:
BLEY KEITH R
BERND JANDELEIT
Application Number:
JP2018067394A
Publication Date:
August 23, 2018
Filing Date:
March 30, 2018
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
ACORDA THERAPEUTICS INC
International Classes:
C07C329/06; A61K9/00; A61K31/265; A61K31/27; A61K47/02; A61P9/10; A61P25/00; A61P25/04; A61P29/00; C07C313/04
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto