ALPHA-(2-AZIDO-2-DEOXYGLYCOYL) CERAMIDE DERIVATIVE

Title:

ALPHA-(2-AZIDO-2-DEOXYGLYCOYL) CERAMIDE DERIVATIVE

Document Type and Number:

Japanese Patent JPS6496

Kind Code:

A

Abstract:

NEW MATERIAL:A compound shown by formula I [one of R1 and R2 is H and the other is lower acyloxy; one of R3 and R4 is H and other is lower acyloxy or pyranosyl of (1→4) bond wherein OH thereof is peracylated with lower acyl; R5 is 10W25C alkyl; R6 is lower acyl; R7 is OH-protecting group; n is 10W25].

EXAMPLE: 2-Azido-2-deoxy-3,4,6-tri-O-acety-α-D-galactopyranosyl 1-1(3-O-benzoyl) ceramide.

USE: An intermediate for an antigen for sensitization.

PREPARATION: A peracyl-2-azide-2-deoxy saccharide halide shown by formula II (X is halogen) is reacted with a ceramide shown by formula III in the presence of molecular sieve and a silver salt catalyst preferably at room temperature.

Inventors:

NAKANO KOICHI
HASHIMOTO HIRONOBU
KANAKI REIJI
KATO TAKAO

Application Number:

JP29515387A

Publication Date:

January 05, 1989

Filing Date:

November 25, 1987

Export Citation:

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Assignee:

TOSOH CORP

International Classes:

C07H15/10; C07H15/04; G01N33/53; G01N33/574; (IPC1-7): C07H15/04; G01N33/53; G01N33/574

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