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Title:
ANGIOTENSIN (AII) RIVALRY SUBSTANCE AS INHIBITOR OF GROWTH OF ADIPOSE TISSUE
Document Type and Number:
Japanese Patent JPH0717862
Kind Code:
A
Abstract:
PURPOSE: To reduce the proliferation of adipocytes and the increase in body weight by administering angiotensin antagonists as inhibitors of the growth of adipose tissue. CONSTITUTION: Angiotensin II receptor in the cell membrane of adipocytes is used to inhibit an adipocyte angiotensin II receptor-blocking agent thereby reducing proliferation of adipocytes and increase in body weight. This is effective for treatment of diseases as adiposity or non-insulin-dependent diabetes. A compound of formula I (Ar is formula II; R is an alkyl; R is an alkyl; R is H, pyrrole) is active as the angiotensin II receptor-blocking agent.

Inventors:
DEIBITSUDO REROI KURANDOORU
Application Number:
JP16468794A
Publication Date:
January 20, 1995
Filing Date:
June 23, 1994
Export Citation:
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Assignee:
AMERICAN CYANAMID CO
International Classes:
A61K31/00; A61K31/41; A61K31/415; A61K31/435; A61K31/44; A61K31/505; A61P3/04; A61P3/08; A61P3/10; C07D403/10; (IPC1-7): A61K31/41; A61K31/415; A61K31/435; A61K31/44; A61K31/505
Attorney, Agent or Firm:
小田島 平吉