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Title:
ANTI-CANCER AGENT, METAL COMPLEX AND HETEROCYCLE COMPOUND
Document Type and Number:
Japanese Patent JP2015020986
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide an anti-cancer agent which is inexpensive because of no use of expensive noble metal, and has mechanisms of action different from conventional platinum formulations.SOLUTION: An anti-cancer agent contains as an active ingredient a metal complex represented by the general formula (1) in the figure. (In the formula, Rrepresents a hydrogen atom, a C-Calkoxy group or an alkyl group or the like; Rrepresents a hydrogen atom, a C-Calkoxy group or the like; Rto Rrepresent hydrogen atoms or the like; M represents iron, manganese or cobalt; X represents a counter ion; and n represents 1 or 2.)

Inventors:
HITOMI YUTAKA
IWAMOTO YUJI
Application Number:
JP2013151507A
Publication Date:
February 02, 2015
Filing Date:
July 22, 2013
Export Citation:
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Assignee:
DOSHISHA
International Classes:
A61K31/4709; A61P35/00; C07D401/14; C07F13/00
Domestic Patent References:
JP2013023474A2013-02-04
JP2004520380A2004-07-08
JP2005041869A2005-02-17
JP2003501432A2003-01-14
Other References:
日本化学会第93春季年会(2013)講演予稿集II, JPN6017010748, March 2013 (2013-03-01), pages 219, ISSN: 0003526635
日本化学会第93春季年会(2013)講演予稿集II, JPN6017010749, March 2013 (2013-03-01), pages 219, ISSN: 0003526636
CANCER. RES., vol. Vol.65(3), JPN6017010750, 2005, pages 948 - 956, ISSN: 0003526637
PEPTITE SCIENCE 2012, JPN6017010752, March 2013 (2013-03-01), pages 279 - 282, ISSN: 0003526638
ANGEW. CHEM. INT. ED., vol. 51, JPN6017010751, 2012, pages 3448 - 3452, ISSN: 0003526639
Attorney, Agent or Firm:
Katsunori Sugimoto
Mitsuhiro Okada