Title:
抗菌性組成物、抗菌性組成物を含む骨再生用材料、及びその製造方法
Document Type and Number:
Japanese Patent JP7083975
Kind Code:
B2
Abstract:
To provide a highly safe silver-based antimicrobial composition that exhibits antimicrobial property early in accord with the decomposition and absorption of calcium compound after a bone regeneration material is implanted in the body and that yet has a low risk of developing cytotoxicity.SOLUTION: By mixing a calcium acetate solution and a silver nitrate solution to generate a white precipitate, followed by adding thereto nitric acid to dissolve and prepare a sample solution, followed by subjecting to ultrasonic spray pyrolysis to produce a hollow approximately spherical calcium carbonate particle in which silver nanoparticles are distributed and deposited approximately homogeneously on the surface, and thereby an antimicrobial inorganic filler is obtained.SELECTED DRAWING: Figure 4
Inventors:
Aizawa Mamoru
Honda Michiyo
Tomohiro Yokota
Mayu Ueda
Masashi Makita
Naoya Osaka
Honda Michiyo
Tomohiro Yokota
Mayu Ueda
Masashi Makita
Naoya Osaka
Application Number:
JP2018108486A
Publication Date:
June 14, 2022
Filing Date:
June 06, 2018
Export Citation:
Assignee:
Meiji University
International Classes:
A01N25/00; A01N59/16; A01N25/12; A01N25/24; A01N25/34; A01P3/00; A61K9/14; A61K33/38; A61K47/02; A61L27/02; A61L27/04; A61L27/12; A61L27/18; A61L27/44; A61L27/46; A61L27/54; A61L27/58; A61P31/04
Domestic Patent References:
| JP2016172656A |
Foreign References:
| WO2017029482A1 | ||||
| WO2015005205A1 |
Other References:
横田倫啓、本田みちよ、大坂直也、牧田昌士、西川靖俊、春日敏宏、相澤守,抗菌性を備えた銀含有リン酸カルシウム微小球の合成とその特性評価,日本バイオマテリアル学会大会予稿集,39,2017年,109
DLUGOSZ Maciej, BULWAN Maria, KANIA Gabriela, NOWAKOWSKA Maria, ZAPOTOCZNY Szczepan,Hybrid calcium carbonate/polymer microparticles containing silver nanoparticles as antibacterial agents,Journal of Nanoparticle Research,2012年,14, 12,1-8
DLUGOSZ Maciej, BULWAN Maria, KANIA Gabriela, NOWAKOWSKA Maria, ZAPOTOCZNY Szczepan,Hybrid calcium carbonate/polymer microparticles containing silver nanoparticles as antibacterial agents,Journal of Nanoparticle Research,2012年,14, 12,1-8
Attorney, Agent or Firm:
Katsuyuki Ninomiya
Kenichi Kobayashi
Kenichi Kobayashi